Exhibit displays the art of scientific imagery
Some species of bacteria live inside leeches, providing their hosts with nutrients. The relationship between these two creatures roused the artistic side of two scientists.Two American Museum of Natural History curators added fluorescent molecules to DNA designed to pair up with the bacterial DNA, and that allowed them to create pictures of bacteria inside adult and juvenile leeches. Some of the bacteria are visible as tiny gold specks.
Nine of the pictures are on display as part of a new, yearlong exhibit at the natural history museum that explores the artistry of scientific images.
Check out this amazing science exhibit
“When you first look at it, it’s really quite abstract," said Mark Siddall, curator of invertebrate zoology at the museum, who with associate curator Susan Perkins created the leech with bacteria images. "I thought this might be something that other people might like to engage with."
The artistic side of science The exhibit, "Picturing Science: Museum Scientists and Imaging Technologies," draws from a wide range of research currently under way at the museum. It includes: an Andy Warhol-style analysis of a meteorite's chemical composition, a bird's-eye view of the Messier 101 galaxy pieced together from images taken by the Hubble Space Telescope , elegant black-and-white images of insect genitalia , and ritual objects stashed within a Tibetan wooden figure.
Color, form and spatial relationships are typically the domain of an artist, but scientists will use these characteristics to explore scientific questions, Siddall said.
Their methods can be fairly low-tech. Three species of fish were still whole when images were made of their insides, but the bones and cartilage stand out sharply thanks to the use of dyes and chemicals to make the other tissues transparent. And an arachnologist needed only ultraviolet light to make ghostly images of scorpions.
Highly sophisticated techniques are also represented. A mathematical simulation of how gas behaves after a star explodes as a supernova generated an image of the orange flames of interstellar gas. The colorful meteorite slices and the insect genitals were both created by bombarding the specimens with electrons (the negatively charged particles in atoms) under sophisticated microscopes.
Looking inside a lizard Edward Stanley, a doctoral candidate in comparative biology at the museum’s Richard Gilder Graduate School, uses computed tomography (CT) scans to look at evolutionary patterns within a family of lizards.
History Of Identifying Unknown Bacteria - News

NEW YORK — Some species of bacteria live inside leeches, providing their hosts with nutrients. The relationship between these two creatures roused the artistic side of two scientists. Two American Museum of Natural History curators added

Eric Boyd of MSU led a team of researchers who discovered the approximate time that bacteria and archaea started producing nitrogen in a useable form. (MSU photo by Kelly Gorham). BOZEMAN - A team of scientists led by has
To better understand the seemingly greater virulence of the outbreak strain, a German team led by Helge Karch from the University of Münster investigated the virulence profiles of the O104:H4 strain by analysing 80 bacteria samples from patients in the

Along with a urinalysis, usually a culture can be ordered (urine culture) that can show the proliferation of bacteria and can identify what is causing the disease. In some cases, especially in children and patients with a history of several UTIs,
What strikes us is that at its core, what we believe may be the most critical component of the BACcel diagnostic system, the component that is responsible for actually identifying the bacteria and determining antibiotic resistance for sick patients,
Bone biopsy is indicated to identify the pathogens in osteomyelitis
A 75-year-old man with type 2 diabetes mellitus is evaluated in the emergency department for a draining chronic ulcer on the left foot, erythema, and fever. Drainage initially began 3 weeks ago. Current medications include metformin and glyburide.
On physical examination, he is not ill appearing. Temperature is 37.9 °C (100.2 °F); other vital signs are normal. The left foot is slightly warm and erythematous. A plantar ulcer that is draining purulent material is present over the fourth metatarsal joint. A metal probe makes contact with bone. The remainder of the examination is normal.
The leukocyte count is normal, and an erythrocyte sedimentation rate is 70 mm/h. A plain radiograph of the foot is normal.
Gram stain of the purulent drainage at the ulcer base shows numerous leukocytes, gram-positive cocci in clusters, and gram-negative rods.
Which of the following is the most appropriate management now?
A) Begin imipenem
Answer and CritiqueThe correct answer is D) Perform bone biopsy. This item is available to MKSAP 15 subscribers as item 8 in the Infectious Disease section.
Contact with bone (when using a sterile, blunt, stainless steel probe) in the depth of an infected pedal ulcer in patients with diabetes mellitus is strongly correlated with the presence of underlying osteomyelitis, with a positive predictive value of 90%. Patients with diabetes require bone biopsy to obtain deep pathogens, identification of which is the only way to establish a definitive diagnosis and guide therapy. Although it may seem intuitive that drainage from a superficial site such as an ulcer or a sinus tract would contain the causative pathogens, superficial cultures usually do not include the deep organisms responsible for the infection. Failure to identify the causative deep-bone pathogens may lead to spread of infection to adjacent bones or soft tissues and the need for extensive debridement or amputation. The one exception is Staphylococcus aureus , which, even if found in superficial cultures, correlates well with findings on deep cultures.
This patient appears well enough to wait for the bone biopsy to be completed before starting empiric antibiotic therapy (and adjusting the antibiotics based on culture results) or until bone culture results become available. Empiric therapy should include activity against streptococci, methicillin-resistant S. aureus (MRSA), aerobic gram-negative bacilli, and anaerobes. Therapy with imipenem alone will not adequately cover MRSA, vancomycin and ceftazidime will not adequately cover anaerobic bacteria, and vancomycin and metronidazole will not adequately cover gram-negative organisms.
History Of Identifying Unknown Bacteria - Bookshelf
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